KMID : 0360319920240060807
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Journal of Korean Cancer Research Association 1992 Volume.24 No. 6 p.807 ~ p.812
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Separation of Acive Chemical Components Against Sarcoma 180 from Stembark of Catalpaovata
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Abstract
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The methanolic extract from stembark of Catalpa ovata(Bignoniaceae) showed a cytotoxic activity on Sarcoma 180 cell lines.
In order to isolate the active compound, a systemic separation was performed.
The result was that chloroform and hexane fraction showed a marked cytotoxic activity.
Active compounds in these two fractions were separated and identified as a-lapachone and 9-hydroxy-a-lapachone and 9-methoxy-a-lapachone.
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